This technology is an innovative glycan library platform for drug development. This is a DNA-encoded glycan library (DEGL) platform demonstrating higher content and throughput potential. Scientists can utilize this platform to identify and study specific glycan structures through unique DNA barcodes, facilitating drug screening and lead optimization processes. Glycans are major players in disease pathogenesis and therefore of diagnostic and therapeutic significance.
Patent Status
US20200109435A1 - Dna-glycan conjugates and methods of use - Google Patents
Publications
DNA Encoded Glycan Libraries as a next-generation tool for the study of glycan-protein interactions - Abstract - Europe PMC