Glycan Binding HTS Platform for Drug Development

Description

This technology is an innovative glycan library platform for drug development. This is a DNA-encoded glycan library (DEGL) platform demonstrating higher content and throughput potential. Scientists can utilize this platform to identify and study specific glycan structures through unique DNA barcodes, facilitating drug screening and lead optimization processes. Glycans are major players in disease pathogenesis and therefore of diagnostic and therapeutic significance.

 

Benefits

  • Affordable and Accessible: Affordable tool to study glycan binding, reducing costs associated with traditional methods such as qPCR and NGS.
  • High Throughput Analysis: Enables rapid screening of glycan binding interactions, allowing the processing of a large number of samples in a short time
  • High Sensitivity and Flexibility: Capable of detecting subtle glycan binding interactions even at low concentrations, ensuring accurate and reliable data.

 

Applications

  • Drug screening
  • Drug discovery
  • Lead optimization
  • Biomedical research

 

Patent Status

 

Publications

DNA Encoded Glycan Libraries as a next-generation tool for the study of glycan-protein interactions - Abstract - Europe PMC

Patent Information:
Category(s):
Assay
Research Tool
For Information, Contact:
Kenneth Franklin
Senior Licensing Associate
Georgia State University
kfranklin31@gsu.edu
Inventors:
George Peng Wang
Muhammed Kondengaden
Aishwarya Parameswaran
Jing Song
Liuqing Wen
Huajie Zhang
Keywords:
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