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Oral Paramyxovirus Therapeutic with Low Toxicity and Reduced Viral Resistance

Description This technology is an RNA polymerase inhibitor therapeutic for use in paramyxoviruses, including parainfluenza, Nipah virus and measles. This allosteric, non-nucleoside inhibitor acts by binding to the polymerase complex to inhibit viral RNA replication and may have lower toxicity than nucleoside polymerase inhibitors. There is currently...

Published: 3/19/2025 | Inventor(s): Richard Plemper, Robert Cox, Benhur Lee

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Category(s): Therapeutics