Search Results - richard+plemper

3 Results

Sort By:

Oral Paramyxovirus Therapeutic with Low Toxicity and Reduced Viral Resistance

Description This technology is an RNA polymerase inhibitor therapeutic for use in paramyxoviruses, including parainfluenza, Nipah virus and measles. This allosteric, non-nucleoside inhibitor acts by binding to the polymerase complex to inhibit viral RNA replication and may have lower toxicity than nucleoside polymerase inhibitors. There is currently...

Published: 3/19/2025 | Inventor(s): Richard Plemper, Robert Cox, Benhur Lee

Keywords(s):

Category(s): Therapeutics

Safer Canine Distemper Virus Vaccine

Description This technology is a much safer, cutting-edge vaccine for canine distemper virus (CDV) that overcomes the potential pathogenicity found in current live CDV vaccines. CDV is a very contagious virus that can cause severe disease in young dogs and is found worldwide. Unfortunately, the mortality rate of canine distemper is about 50% in dogs...

Published: 11/4/2024 | Inventor(s): Richard Plemper, Veronika vonMessling

Keywords(s):

Category(s): Vaccine

Highly Sensitive RSV Reporter Tools for Anti-Viral Drug Discovery

Description This technology is a series of innovative RSV reporter tools for high throughput screening of anti-viral drug candidates. Our reporter tools offer innovative solutions for RSV drug discovery and vaccine development, with improved sensitivity and robustness compared to conventional fluorescent assays. Additionally, these tools are simplified,...

Published: 3/24/2025 | Inventor(s): Richard Plemper

Keywords(s): Virus

Category(s): Research Tool