Search Results - research+tool

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Hydrogen Sulfide-Releasing Therapeutics Reduce NSAID Toxicity and Provide Protection During Stroke

Description This technology is a suite of hydrogen sulfide (H2S) prodrugs that has broad applicability for decreasing toxicity during the treatment of inflammation using NSAIDs. In vivo studies have demonstrated reduction of gastrointestinal ulcers, kidney toxicity, and liver toxicity during NSAID use. In separate in vivo studies, these technologies...

Published: 3/24/2025 | Inventor(s): Binghe Wang, Yueqin Zheng

Keywords(s):

Category(s): Therapeutics, Research Tool

Faster, More Accurate, Mouse Behavior Tracking Tool

Description This technology is a software tool to automate the recognition, extraction and tagging of mouse behaviors over an extended timeframe in a comprehensive and objective fashion. Neurobehavioral analysis of mouse phenotypes – especially home cage behaviors, such as those related to maternal care – is essential for numerous research...

Published: 3/24/2025 | Inventor(s): Jessica Bolton, Ashwin Ashok, Sridutt Kalidindi

Keywords(s):

Category(s): Research Tool, Software

Glycan Binding HTS Platform for Drug Development

Description This technology is an innovative glycan library platform for drug development. This is a DNA-encoded glycan library (DEGL) platform demonstrating higher content and throughput potential. Scientists can utilize this platform to identify and study specific glycan structures through unique DNA barcodes, facilitating drug screening and lead...

Published: 2/21/2025 | Inventor(s): George Peng Wang, Muhammed Kondengaden, Aishwarya Parameswaran, Jing Song, Liuqing Wen, Huajie Zhang

Keywords(s):

Category(s): Assay, Research Tool

Highly Specific Cartilage-Targeting Imaging Agents for Early Detection of Arthritis

Description This technology is a new class of dyes designed for cartilage-specific imaging in the near-infrared-II (NIR-II) window. Currently, there is a lack of tissue-specific diagnostic methods for early detection of arthritis, and of clinically available, high quality, cartilage contrast agents. This lack of early diagnostic capability means that...

Published: 2/21/2025 | Inventor(s): Maged Henary, Hak Soo Choi, Homan Kang

Keywords(s):

Category(s): Imaging, Research Tool

Highly Sensitive RSV Reporter Tools for Anti-Viral Drug Discovery

Description This technology is a series of innovative RSV reporter tools for high throughput screening of anti-viral drug candidates. Our reporter tools offer innovative solutions for RSV drug discovery and vaccine development, with improved sensitivity and robustness compared to conventional fluorescent assays. Additionally, these tools are simplified,...

Published: 3/24/2025 | Inventor(s): Richard Plemper

Keywords(s): Virus

Category(s): Research Tool