Search Results - maged+henary

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Selective Chemotherapeutics That Specifically Target Tumor Cells

Description This technology is a series of synthesized cyanines that display high binding affinity to quadruplex DNA with high selectivity over duplex sequences. Cyanines are a class of small molecules that could be developed as potential G-quadruplex targeting agents. These cyanines have been designed to achieve highly selective binding to DNA G-quadruplexes...

Published: 2/21/2025 | Inventor(s): Maged Henary, W. David Wilson

Keywords(s):

Category(s): Therapeutics

Highly Specific Cartilage-Targeting Imaging Agents for Early Detection of Arthritis

Description This technology is a new class of dyes designed for cartilage-specific imaging in the near-infrared-II (NIR-II) window. Currently, there is a lack of tissue-specific diagnostic methods for early detection of arthritis, and of clinically available, high quality, cartilage contrast agents. This lack of early diagnostic capability means that...

Published: 2/21/2025 | Inventor(s): Maged Henary, Hak Soo Choi, Homan Kang

Keywords(s):

Category(s): Imaging, Research Tool

Low-Cost Detection of Retained Surgical Items Before Closure

Description This technology is an innovative platform to detect surgical items retained in the human body, including sponges, gauzes, cottonoids, scalpels, needles, and others. Surgical items retained in the body create a variety of health, legal and monetary consequences. For the patient, the result can be infection, blood poisoning, organ failure...

Published: 1/24/2025 | Inventor(s): Maged Henary, Jordan Malray

Keywords(s):

Category(s): Imaging

Low Energy Photosensitizers with Improved Safety and Efficacy for Dermatological Conditions Description

Description This technology is a group of novel photosensitizers used in photodynamic therapy to treat cancer, dermatological conditions, and other cell growth disorders, including elective cosmetic treatments. Photosensitizers are a critical component of photodynamic therapy as they produce a reactive form of oxygen when exposed to a specific wavelength...

Published: 1/24/2025 | Inventor(s): Maged Henary, Kathryn Grant

Keywords(s):

Category(s): Therapeutics

Deep Tissue Imaging Agents With Improved Tumor-Killing Capabilities

Description This technology is a set of novel near-infrared (NIR) fluorescent compounds for simultaneously imaging and killing cancer cells. NIR fluorescence is an emerging biomedical imaging technique that has the potential to provide surgeons with highly specific images of the target tissues. Improved bioimaging systems with deeper tissue penetration...

Published: 8/28/2024 | Inventor(s): Maged Henary

Keywords(s):

Category(s): Diagnostic, Therapeutics